Following is a list of publications and conference presentations by OAML Research Trust Small Grants recipients. The OAML is pleased to have provided support to these outstanding scientists and their work.

Dr. Khosrow Adeli, Hospital for Sick Children

Mohammadi A, Macri J, Dulay D, Romain T, Newton R and Adeli K. Effects of atorvastatin on intracellular stability and secretion of apolipoprotein B in HepG2 cells. Arterioscl. Thromb. Vas. Biology. 18:783-793, 1998.

Macri J, Thibert RJT and Adeli K. Hepatic production of apolipoprotein B containing lipoproteins: Mechanisms and Modulators. Fats of Life (AACC Lipids and Lipoproteins Division) XI (4): 1-10, 1997.

Dr. Hong Chang, Princess Margaret Hospital, University Health Network

Hong Chang, Ashutosh Wechalekar, Linda Li, Donna Reece. Molecular Cytogenic Abnormalities in Patients with Concurrent Chronic Lymphocytic Leukemia and Multiple Myeloma Shown by Interphase Fluorescence in Situ Hybridization: Evidence of Distinct Clonal Origin. Cancer Genetics and Cytogenetics, 148 (2004) 44-48.

Dr. Karen Harrison, Kingston General Hospital

CJ Forster-Gibson, Leanne Mercer and Karen Harrison. Similar Physical and Behavioural Phenotypes in Two Men with dup(17)(p11.2p11.2). The Society for the Study of Behavioural Phenotypes Annual General Meeting, November, 2002.

Dr. Barry Hoffman, Mount Sinai Hospital

Bhupinder Bharaj, Andreas Scorilas, Eleftherios Diamandis, Maurizia Giai, Michael A. Levesque, Donald J. A. Sutherland, and Barry R. Hoffman. Breast cancer prognostic significance of a single nucleotide polymorphism in the proximal androgen response element of the prostate specific antigen gene promoter. Breast Cancer Research and Treatment 61:111-119 (2000).

Hoffman BR, Scorilas A, Diamandis EP, Giai M, Levesque MA, Bharaj B. A prevalent polymorphism in the proximal androgen response element of the prostate specific antigen gene and its implications in breast cancer prognosis. Abstract # 596 at the 91st Annual Meeting of the American Association for Cancer Research, April 2000.

Dr. John A Kiernan, University of Western Ontario

Kiernan, J. A., Macpherson, C. M., Price, A. & Sun, T. 1998. A histochemical examination of the staining of kainate-induced neuronal degeneration by anionic dyes. Biotechnic & Histochemistry 73, 244-254.

Conway, K. & Kiernan, J. A. 1999. Chemical dehydration of specimens with 2,2-dimethoxypropane (DMP) for paraffin processing of animal tissues: practical and economic advantages over dehydration in ethanol. Biotechnic & Histochemistry 74, 20-26.

Dr. Denis Macdonald, Sunnybrook and Women's College Health Sciences Centre

Macdonald D, Paterson M, Pimlott N, Danacic R. "Management of Oral Anticoagulant Therapy in the Community - A comparison of academic and community practice in Ontario." XIVth International Symposium on Technological Innovations in Laboratory Hematology, Montpellier, France, May 2001.

Macdonald D, Paterson M, Pimlott N, Danacic R. "Management of Oral Anticoagulant Therapy in the Community- Evaluation of a new statistical method." XIVth International Symposium on Technological Innovations in Laboratory Hematology, Montpellier, France, May 2001.

Dr. Rosemary Mueller, Samuel Lunenfeld Research Institute, Mt. Sinai Hospital

Rosemary E. Mueller, Robert K. Parkes, Frances P. O'Malley. "Determination by FISH of HER2 amplification status in clinical breast tumour samples: a novel statistical approach using distribution markers." Poster presentation, Research Day for the Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario. September, 2003.

Rosemary E. Mueller, Robert K. Parkes, Frances P. O'Malley.  "Defining Useful Cut-offs for HER2 FISH Analysis in Clinical Breast Samples." American College of Medical Geneticists Meeting, March 4-7, 2004.

Dr. Peter Ray, Hospital for Sick Children

Annette Feigenbaum, Robert Moore, Joe Clarke, Stacy Hewson, David Chitayat, Peter N. Ray and Tracy L. Stockley, "Canavan Disease: Carrier-Frequency Determination on the Ashkenazi Jewish Population and Development of a Novel Molecular Assay."  In press, 2004.

Dr. Andrew Simor, Sunnybrook and Women's College Health Sciences Centre

Louie, L., Goodfellow, J., Mathieu, P., Glatt, A., Louie, M. and Simor, A. E. Rapid Detection of Methicillin-Resistant Staphylococci from Blood Culture Bottles by Using a Multiplex PCR Assay, Journal of Clinical Microbiology: 40, 8. 2786-2790. August 2002.

L. Louie, J. Goodfellow, P. Mathieu, A. Glatt, M. Louie & A.E. Simor. "Rapid Detection of Methicillin-Resistant Staphylococcus aureus directly from Blood Cultures Using Multiplex PCR." Abstract C-25, American Society for Microbiology, Orlando, Florida, May 20-24, 2001.

Dr. Ikuko Teshima, Hospital for Sick Children

Clarkson B, Pavenski K, Dupuis L, Kennedy S, Meyn S, Nezarati M, Nie G, Weksberg R, Withers S, Quercia N, Teebi AS, Teshima I: Detecting rearrangements in children using subtelomeric FISH and SKY. American Journal of Medical Genetics 2002: 107: 267-274.

May 18, 2000. Great Lakes Chromosome Conference, Toronto, Ontario. "Subtelomeric FISH."

June 7, 2000. Association of Genetic Colleagues of Ontario, annual meeting. Kingston, Ontario. "Spectral karyotyping and subtelomeric FISH."

November 24, 2000. Canadian College of Medical Geneticists, annual symposium, Whistler, British Columbia. "Hot, new technological advances: subtelomeric FISH."

April 4, 2002. Genetic Rounds, Hospital for Sick Children, Toronto. "Introducing Telomeric FISH into Clinical Practice." (Introduced this test as service on April 1, 2002

Dr. Carl van Walraven, University of Ottawa.  Dr. van Walraven was an Ontario Ministry of Health Career Scientist.

Carl van Walraven and Mike Raymond for the Network of Eastern Ontario Medical Laboratories (NEO-MeL), "Population-based Study of Repeat Laboratory Testing." Clin Chem 2003 49:12, 1997-2005.

Carl van Walraven, MD, FRCPC, MSc, Geta Cernat and Peter C. Austin, PhD for the Network of Eastern Ontario Medical Laboratories (NEO-MeL), "Why are laboratory tests repeated? The role of multiple physicians treating the same patient."  Submitted for publication.

Carl van Walraven, Geta Cernat and Peter Austin, "Effect of Provider Continuity on Test Repetition". Clinical Chemistry 52:12, 2219-2228 (2006)

Dr. Chen Wang, Mount Sinai Hospital

Wang, C., Amato, D. and Fernandes, B. CD-5 Negative Phenotype of Monoclonal B-Lymphocytosis of Undetermined Significance (MLUS). American Journal of Hematology 69: 147-149, 2002.